Evaluation of vaccines

NOD/scid IL-2Rgnull mice: a preclinical model system to evaluate human dendritic cell-based vaccine strategies in vivo.  Spranger S, Frankenberger B, Schendel DJ.  J Transl Med. 2012 Feb 25;10:30.  PMID: 22364226

Humoral immune responses in humanized BLT mice immunized with West Nile virus and HIV-1 envelope proteins are largely mediated via human CD5+ B cells.  Biswas S, Chang H, Sarkis PT, Fikrig E, Zhu Q, Marasco WA.  Immunology. 2011 Dec;134(4):419-33. doi: 10.1111/j.1365-2567.2011.03501.x.  PMID: 22044090

Inhibition of in vivo HIV infection in humanized mice by gene therapy of human hematopoietic stem cells with a lentiviral vector encoding a broadly neutralizing anti-HIV antibody.  Joseph A, Zheng JH, Chen K, et al. J Virol. Jul 2010;84(13):6645-6653.  PMID: 20410262, PMCIC: PMC2903239

Induction of robust cellular and humoral virus-specific adaptive immune responses in human immunodeficiency virus-infected humanized BLT mice.  Brainard DM, Seung E, Frahm N, et al. J Virol. Jul 2009;83(14):7305-7321.  PMID: 19420076, PMCID:PMC2704767